Figure 1: Female and male BTBR mice exhibit an altered gut microbial composition. | Scientific Reports

Figure 1: Female and male BTBR mice exhibit an altered gut microbial composition.

From: Sex-related alterations of gut microbiota composition in the BTBR mouse model of autism spectrum disorder

Figure 1

(A) Unweighted UniFrac-based 3D PCoA plot constructed on all OTUs (32,288 reads per sample, left) or all OTUs without Bacteroidetes and Firmicutes reads (850 reads per sample, right) of fecal community of BTBR and C57 mice of both sexes. Analysis of similarity (ANOSIM) with 999 permutations was used to detect the statistical significant differences in microbial community composition between fBTBR and mBTBR compared to their controls (fC57 and mC57); on the top of plots are reported both R statistics and p values. (B) Relative abundance of all identified OTUs classified at phylum level. Mean values ± SEM are plotted (n = 6/group). Significant differences are indicated by *p < 0.05 and **p < 0.01 for comparison of fBTBR vs. fC57 and mBTBR vs. mC57. Abbreviations: fBTBR (BTBR female mice); mBTBR (BTBR male mice); fC57 (C57 female mice); mC57 (C57 male mice).

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