Figure 1: Conceptual approach and device design of the Cellarium technology.
From: A platform for high-throughput bioenergy production phenotype characterization in single cells

(A) Single cells are enclosed in hermetically sealed microchambers that contain an extracellular thin-film optical sensor. The sensor emission intensity changes in real time in response to alterations in analyte concentration inside the chamber; (B) A microwell array of 4,096 microwells used in the study. The arrays are microfabricated in glass and are optically transparent for readout; (C) A transmission light micrograph of a region of the microwell array. Scale bar: 200 μm.