Table 4 Genes whose expression is modulated by 3 nM ouabain and 30 nM MBG after 96-h incubation.

From: Time- and dose dependent actions of cardiotonic steroids on transcriptome and intracellular content of Na+ and K+: a comparative analysis

Gene symbol

Affymetrix ID

3 nM ouabain, fold of modulation/p-value

30 nM MBG, fold of modulation/p-value

FOS

7975779

33.28/8.84E-07

13.29/4.84E-06

ZFP36

8028652

20.36/9.39E-07

6.09/7.00E-06

EGR1

8108370

15.33/3.86E-05

21.43/6.11E-08

ADAMTS1

8069676

13.04/8.84E-07

5.01/4.04E-04

PTGS2

7922976

11.36/1.38E-06

9.02/4.46E-06

EGR2

7933872

8.09/9.39E-07

10.19/6.06E-07

ATF3

7909610

7.39/6.40E-06

8.13/5.14E-06

ARRDC4

7986350

5.62/2.45E-06

NC

NR4A1

7955589

5.39/2.13E-05

7.29/3.30E-06

NR4A3

8156848

5.38/2.09E-05

6.00/5.25E-05

STC1

8149825

5.35/4.84E-04

NC

JUNB

8026047

5.06/3.43E-06

1.53/5.87E-03

KLF4

8163002

4.70/3.66E-05

3.03/1.21E-04

DUSP1

8115831

4.52/3.32E-06

6.09/3.33E-05

ADAMTS5

8069689

4.43/2.58E-05

2.16/2.01E-03

NR4A2

8055952

4.15/1.28E-04

2.99/4.56E-04

SNAI1

8063382

3.87/8.20E-06

NC

HEY1

8151457

3.75/1.21E-05

1.84/9.12E-03

SOCS3

8018864

3.75/7.12E-06

NC

VTRNA1–3

8108631

3.64/5.49E-05

2.76/3.12E-04

JUN

7916609

3.17/6.40E-06

4.72/3.60E-05

KITLG

7965322

3.05/3.99E-05

1.44/8.66E-03

C7orf53

8135532

3.00/6.76E-04

1.33/8.66E-03

EGR3

8149720

2.98/1.48E-04

3.07/3.09E-04

GDF15

8027002

2.98/9.39E-07

NC

IDI2

7931748

2.87/1.55E-03

NC

BAMBI

7926875

2.80/4.30E-04

1.29/1.68E-02

EFNB2

7972713

2.79/1.44E-05

1.52/6.33E-03

GEM

8151816

2.77/6.90E-04

2.71/7.67E-04

ABCG2

8101675

2.76/2.27E-06

NC

SNORD3A

8005547

2.72/2.03E-05

NC

FAM71A

7909624

2.66/1.36E-04

1.70/4.02E-04

IER2

8026163

2.65/8.00E-05

1.54/9.03E-03

HIST2H2BE

7919637

2.60/1.13E-04

1.67/7.66E-04

INSIG1

8137526

2.58/1.44E-05

1.25/9.33E-03

PROX1

7909681

2.52/2.45E-06

2.70/5.01E-04

HEY2

8121850

2.52/1.32E-04

2.07/9.81E-04

CA8

8150978

2.50/1.28E-03

NC

HIST1H1T

8124402

2.48/7.76E-03

1.32/8.08E-03

TNFSF9

8025053

2.47/1.45E-04

3.71/9.91E-05

DLL4

7982854

2.46/1.30E-05

NC

PTHLH

7962000

2.39/8.00E-05

NC

APOLD1

7954055

2.36/4.48E-04

NC

GUCY1B3

8097973

2.34/1.01E-05

NC

IGFBP5

8058857

2.28/8.16E-03

1.60/4.00E-03

SPRY4

8114797

2.28/2.56E-03

1.79/2.83E-03

BCL6

8092691

2.27/2.27E-06

NC

HIST2H4A

7905067

2.24/1.01E-04

1.88/4.31E-03

KCNJ2

8009502

2.24/8.00E-05

2.00/7.01E-04

TSC22D2

8083324

2.24/6.58E-05

NC

DDIT3

7964460

2.23/1.06E-03

2.78/3.33E-04

C2orf61

8052004

2.23/1.61E-03

NC

HIST1H2BG

8124423

2.19/7.34E-03

NC

HES1

8084880

2.19/2.45E-06

2.21/4.41E-04

ELMOD1

7943562

2.18/1.25E-04

NC

MAFB

8066266

2.16/9.95E-04

1.89/2.08E-03

HIST1H2BD

8117382

2.13/2.18E-03

NC

SNORD75

7922416

2.11/6.89E-04

−1.39/8.88E-03

ADAMTS9

8088560

2.10/1.30E-05

2.09/7.51E-04

ADAMTS4

7921821

2.09/2.67E-04

1.97/8.31E-04

KLF5

7969414

2.07/6.49E-04

1.62/1.51E-03

HIST2H2AA3

7905079

2.05/1.30E-04

NC

NEFM

8145361

2.04/6.82E-03

−1.25/6.77E-03

PCDH17

7969330

2.04/1.13E-04

NC

TXNIP

7904726

2.03/1.30E-05

2.22/6.89E-04

FJX1

7939365

2.03/2.41E-02

−1.33/9.38E-03

BHLHE40

8077441

2.03/1.80E-05

NC

ID2

8040103

2.02/2.60E-03

1.73/2.21E-05

G0S2

7909441

2.02/3.87E-04

2.06/7.66E-05

IDI1

7931754

2.01/1.39E-04

1.21/4.61E-03

MIRLET7C

8067944

−2,03/3.36E-03

NC

DTL

7909568

−2.05/8.00E-05

NC

KIAA1370

7988970

−2.07/4.94E-06

1.22/2.99E-03

FAM111B

7940147

−2.18/2.72E-03

−1.59/2.27E-03

PDK4

8141094

−2.32/4.18E-05

−1.48/8.72E-04

TRA2A

8138592

−2.40/3.39E-04

NC

EIF5

7977058

−2.52/6.54E-05

−2.59/4.72E-05

FBXO32

8152703

−2.71/1.95E-04

−1.73/3.70E-04

  1. The table lists transcripts whose expression was changed in ouabain-treated cells by more than 2.0-fold.
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