Table 1 Binding affinities of derCD23 to IgE-Fc studied by ITC.

From: IgE binds asymmetrically to its B cell receptor CD23

Experiment

KD1 (μM)

ΔH1 (kcal/mol)

−TΔS1 (kcal/mol)

KD2 (μM)

ΔH2 (kcal/mol)

−TΔS2 (kcal/mol)

derCD23 titrated into IgE-Fc

1.2 ( ± 0.3)

−7.2 ( ± 0.4)

−0.9

14.4 ( ± 3.0)

−3.7 ( ± 0.6)

−3.0