Table 1 Inhibitory effects of UA ester derivatives against α-glucosidase from baker’s yeast.

From: Synthesis and biological evaluation of novel ursolic acid analogues as potential α-glucosidase inhibitors

Compound code

R

IC50a (μM)

Binding free energy (kcal/mol)

UA

H

5.08 ± 0.70

−3.007

UA-01

4.98 ± 0.21

−2.983

UA-02

2.51 ± 0.02

−3.305

UA-03

6.72 ± 0.33

−2.814

UA-04

3.94 ± 0.10

−3.114

UA-05

15.23 ± 0.47

−3.433

Acarboseb

—

569.43 ± 9.98

−9.134

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