Figure 3: Analysis of NCCM. | Scientific Reports

Figure 3: Analysis of NCCM.

From: Molecular Therapy for Degenerative Disc Disease: Clues from Secretome Analysis of the Notochordal Cell-Rich Nucleus Pulposus

Figure 3

(A) Schematic representation of the methodology for identification of proteins in NCCM using mass - spectrometry. (B) Pie-chart showing distribution of ECM proteins identified in NCCM. (C) Peptide signature peaks for CTGF, WISP2 and TGFβ1 observed in mass – spectrometry analysis of NCCM. (D) Immunohistochemistry showing expression of CTGF, WISP-2 and TGFβ1 in paraffin-embedded sections of rat NP (healthy and injured discs) and human degenerative disc NP (Scale bar 50μ).

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