Figure 7: Increased exosomal HOTAIR in obese subjects with sedentary lifestyle.

Eighty-nine physically healthy female subjects were recruited and divided into 4 groups based on their BMI and sedentary lifestyle: Lean (n = 26), Lean + sedentary lifestyle (n = 15), Obesity (n = 20), and Obesity + sedentary lifestyle (n = 28). Relative expression of exosomal HOTAIR was analyzed by RT-qPCR, with the lowest expression level set as value 1. *P < 0.05, ***P < 0.005 as analyzed by One way ANOVA with Tukey’s post hoc analysis.