Figure 1
From: Structure- and conformation-activity studies of nociceptin/orphanin FQ receptor dimeric ligands
Synthesis of homodimer 1: (i) CH3CN/H2O 50:50, NaHCO3 (cat), rt, 12 h. Compounds 2–9, 11, 13 were obtained under the same experimental conditions starting from the corresponding monomer.
