Figure 5: Accumulation of ubiquitinated proteins in aged octodons.
From: Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model
(A) Representative ubiquitin immunoblot in the mesencephalon. [Ub]n: poly-ubiquitinated proteins. Ub: monomeric ubiquitin. (B–D) Levels of poly-ubiquitinated proteins in tissue homogenates from (B) the substantia nigra (SN), (C) the striatum (STR), (D) cortex (Ctx). SN present a significant age-dependent accumulation of poly-ubiquitinated proteins [F(3,11) = 8.703, p = 0.003]. *p < 0.05.
