Figure 4: Physicochemical properties of antimalarial compounds versus herbicides.

Representative charts (A–C) were extracted using an interactive database containing the physicochemical properties of 334 commercial herbicides²⁶. New data points (i.e. compounds studied here) were added to the database and plotted on graphs comparing two chemical properties, (A) molar mass vs lipophilicity (Log P), (B) molar mass vs aqueous solubility (Log S), (C) distribution coefficient (Log D) vs polar surface area (Ų) and (D) molar mass vs polar surface area (Ų). Cluster analyses show the general trends into which the antimalarial compounds fall. Black dots represent the antimalarial compounds that significantly inhibited plant growth, whereas solid grey dots represent antimalarial compounds with poor or no herbicidal activity. Transparent dots represent the 334 herbicidal compounds of the original database²⁶.