Table 6 Comparison of conjunctival hemodynamic descriptors in venules between C and DR subjects in unadjusted (Model 1) and adjusted (Model 2) models.

From: Assessment of Conjunctival Microvascular Hemodynamics in Stages of Diabetic Microvasculopathy

 

D (μm)

V (mm/s)

Q (pl/s)

WSR (s−1)

WSS (dyne /cm2)

β

P

β

P

β

P

β

P

β

P

Intercept

20

<0.001

0.59

<0.001

173

<0.001

183

<0.001

4.8

<0.001

Model 1: DR Stage Effect*

C

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

NDR

1.2

0.03

−0.05

0.2

5

0.8

−29

0.01

−1.1

0.001

NPDR

1.4

0.02

−0.01

0.7

25

0.1

−19

0.1

−0.9

0.008

PDR

0.4

0.52

−0.06

0.1

4

0.8

−29

0.02

−1.2

<0.001

Intercept

19

<0.001

0.49

0.004

151

0.05

185

0.001

3.4

0.03

Model 2: DR Stage Effect**

C

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

NDR

1.4

0.03

−0.06

0.2

7

0.7

−33

0.01

−1.1

0.004

NPDR

2.1

0.006

−0.03

0.6

26

0.2

−29

0.05

−1.1

0.02

PDR

1.1

0.19

−0.11

0.04

−6

0.8

−47

0.003

−1.4

0.002

  1. C, NDR, NPDR, and PDR are abbreviations for non-diabetic control, no clinically visible diabetic retinopathy, non-proliferative diabetic retinopathy, and proliferative diabetic retinopathy, respectively. D, V, Q, WSR, and WSS are abbreviations for diameter, axial blood velocity, blood flow, wall shear rate and wall shear stress, respectively. Bold indicates statistical significance.
  2. *Unadjusted.
  3. **Adjusted for age, race, sex, mean arterial pressure, heart rate, hematocrit, and hemoglobin A1C.