Figure 2: The boxplot of serum alpha-fetoprotein (AFP) levels in pretreatment hepatoblastoma patients (HB (pre-)), patients with benign hepatobiliary disease (BHD), normal controls (NC), HB patients during treatment (HB (during)) and HB patients in remission (HB (remission)).

The box indicates the 25th and 75th percentile values, and the line indicates the median level, whereas the interquartile range (IQR) extends outside the box. The points outside the IQR are mild outliers and the stars outside the IQR are extreme outliers. AFP levels in HB pretreatment group were significantly higher than those in both BHD and NC groups (P < 0.0001 for both). And there was no significant difference in AFP levels between BHD and NC groups (p = 0.1269). There was a significant difference in AFP levels among HB pretreatment, during treatment, and remission groups (p < 0.0001 for all two comparisons).