Figure 1: Breast carcinoma HER-2 immunohistochemistry (IHC).
From: Relevance of deep learning to facilitate the diagnosis of HER2 status in breast cancer
(a) Low-resolution view of a breast carcinoma tissue section stained by HER-2 IHC (brown) and haematoxylin (blue). The overall HER-2 status for this case has been determined as equivocal by a pathologist and it displays important HER2 staining heterogeneity. Solid line and dotted line rectangles corresponds to areas shown in (b) and (c), respectively. Scale bar: 1 mm. (b) Clusters of tumour cells surrounded by immune infiltration and stroma. The majority of cancer cells display a moderate (2+) HER-2 expression. (c) Clusters of tumour cells with strongly positive HER-2 expression (3+) surrounded by stroma.
