Table 1 Clinical Characteristics.

From: Novel Wavelet Real Time Analysis of Neurovascular Coupling in Neonatal Encephalopathy

Gestation Age (weeks)

Birth Weight (Kg)

Sarnat Stage

Sex

Gas Base Deficit

aEEG Pattern

aEEG SWC (cycle/hour)

aEEG Bandwidth (μV)

NIRS SctO2 (Mean)

MRI

Bayley III at 18–24 m

^38

3.3

1

F

19

1

0.6

11

75

0

105-99-95

^37

2.5

1

M

21

1

1

13

76

0

90-97-107

41

3.5

2

M

16

1

0.8

8

76

0

90-95-97

37

3.0

2

M

17

1

0.7

6

80

0

95-98-105

38

3.5

2

F

17

2

None

7

89

0

65-95-82

37

2.9

2

M

20

1

0.5

10

90

(1a)

80-70-90

38

3.1

2

M

22

2

1

9

86

(1b)

71-70-85

38

2.8

3

F

16

1

0.7

11

82

(1b)

90-75-97

38

4.7

2

M

19

2

0.5

9

70

0

70-85-85

36

2.6

2

F

30

3

None

9

88

(2)

65-80-85

  1. ^Denotes the 2 controls who did not receive hypothermia. Clinical severity of encephalopathy using modified Sarnat staging listed as follows: 1, no encephalopathy, 2: moderate NE, 3: severe NE (in a minimum of 3/6 categories). Infants highlighted in grey had the abnormal outcomes. aEEG score 1: continuous, 2, Discontinuous, 3, Burst Suppression. SWC sleep wake cycle. MRI NICHD scores: 0 = no injury; 1a = minimal cerebral lesions only and no area of watershed infarction; 1b = more extensive cerebral lesions, 2 = basal involvement or watershed infarction noted without any other cerebral lesions, 2 = involvement of basal ganglia or infarction and additional cerebral lesions. Bayley outcomes for cognitive-language-motor scores are listed sequentially.
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