Figure 1: IFN-γ release to QFT antigens, 10 screened Mtb specific antigens and selected regions within antigens.
From: Introducing the ESAT-6 free IGRA, a companion diagnostic for TB vaccines based on ESAT-6
Diluted whole blood from 48 patients with TB (A) 34 Egyptian and 14 from Greenland), 18 Mtb infected controls from Greenland (B) and 56 uninfected controls from Egypt (C) was stimulated 24 hours with overlapping peptides (as described in Table 1) in 200 ul volume. IFN-γ release was determined using in-house ELISA and presented following subtraction of IFN-γ release in an unstimulated control well. Median values are indicated in red.
