Table 2 Responder rates in TB patients, LTBI and controls. A responder is defined as antigen-specific release >50 pg/ml IFN-γ.

From: Introducing the ESAT-6 free IGRA, a companion diagnostic for TB vaccines based on ESAT-6

Antigen, n (%)

TB (n = 48)

LTBI (n = 18)

Ctrl (n = 56)

ESAT-6

19 (40)

9 (50)

0 (0)

CFP1

27 (56)

11 (61)

0 (0)

TB7.7

3 (6)

1 (6)

1 (2)

PPE68

1 (2)

0 (0)

3 (5)

EspJ

5 (10)

0 (0)

1 (2)

EspC

22 (46)

8 (44)

1 (2)

EspF

11 (23)

6 (33)

2 (4)

EccD1-A

6 (13)

4 (22)

2 (4)

EccD1-B

2 (4)

4 (22)

1 (2)

PE35-A

2 (4)

1 (6)

1 (2)

PE35-B

3 (6)

3 (17)

1 (2)

Rv2348-A

5 (10)

0 (0)

0 (0)

Rv2348-B

6 (13)

8 (44)

2 (4)