Table 1 Solubility of microcrystalline ZPF, mono-ground ZPF and the corresponding physical mixtures (ZPF + CB[7] and ZPF + β-CD) and co-ground dispersions (ZPF−CB[7], ZPF−β-CD) in pure water, SGF and SIF at 37 ± 0.1 °C after 72 h.

0.018 ± 0.003

0.003 ± 0.001

2.23 ± 0.132

0.021 ± 0.005

0.005 ± 0.001

2.37 ± 0.051

0.023 ± 0.004

0.008 ± 0.002

1.19 ± 0.035^&

0.090 ± 0.008^*

0.022 ± 0.004^#

1.45 ± 0.041^&

0.025 ± 0.005

0.009 ± 0.003

1.28 ± 0.079^&

0.093 ± 0.007^*

0.022 ± 0.006^#

1.49 ± 0.086^&

0.076 ± 0.006^*

0.052 ± 0.005^#

1.23 ± 0.082^&

0.101 ± 0.013^*

0.063 ± 0.006^#

1.58 ± 0.051^&