Figure 5

Intracellular ROS levels induced by various formulations including untreated control (a), blank LPN (b), PTX+TET(c), P/LPN+T (d), P/iRGD LPN+T (e), P+T/LPN (f), and P+T/iRGD LPN (g) with equivalent concentrations of both PTX and TET at 10 μM for 24 h measured by FCM (A) and quantified by relative fluorescence intensity (B). (Various groups vs untreated control #p < 0.05, P+T/LPN vs P+T/iRGD LPN ‡p < 0.05).