Figure 7

Cell cycle distribution (A) and caspase 3/7 activity (B) of A2780/PTX cells treated by various formulations including untreated control (a), blank LPN (b), PTX+TET(c), P/LPN+T (d), P/iRGD LPN+T (e), P+T/LPN (f), and P+T/iRGD LPN (g) with equivalent concentrations of both PTX and TET at 10 μM after 48 h incubation. (Various groups vs free P+T ^#p < 0.05, P+T/LPN vs P+T/iRGD LPN ^‡p < 0.05.) (C) Tubulin immunofluorescence images of A2780/PTX cells treated by various formulations including free PTX, PTX+TET, P+T/LPN, and P+T/iRGD LPN with equivalent concentrations of both PTX and TET at 10 μM for 24 h.