Figure 1: RGC32 was overexpressed and was associated with poor survival in CRC patients.
From: RGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC
(A) The expression of RGC32 mRNA in normal and tumor tissues of patients with CRC was detected with real-time PCR. (B) Kaplan–Meier analysis of overall survival in patients with CRC. (C) Representative images of RGC32 expression in normal intestinal epithelium and CRC specimens examined by IHC. RGC32 was not detected (a, b) in normal intestinal epithelial cells, whereas it was detected in CRC cells (c and d display weak signals, e and f display moderate signals, and g and h display strong signals). *P < 0.05, ***P < 0.001 compared with the score of RGC32 in normal tissue.
