Figure 5: The Smad/Sip1 signaling pathway mediated RGC32-induced EMT in CRC. | Scientific Reports

Figure 5: The Smad/Sip1 signaling pathway mediated RGC32-induced EMT in CRC.

From: RGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC

Figure 5

(A,B) Knockdown of endogenous Sip1 in SW620 cells shown by RT-PCR and western blotting. (C) The expression of mesenchymal and epithelial markers in SW620 cells transfected with scramble (Ctrl) or Sip1 siRNA (siSip1) was detected by western blotting. (D,E) In vitro scratch wound-healing assays and migration assays were performed to investigate the role of Sip1 in CRC cell migration. *P < 0.05, **P < 0.01, ***P < 0.001 vs ctrl.

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