Figure 3: Probands with multiple hits of putative interest. | Scientific Reports

Figure 3: Probands with multiple hits of putative interest.

From: Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairment

Figure 3

(a) Proband 19. Rare AUTS2 variant, stop and rare variant in OR52B2, rare variants in KIAA0586 and STARD9. Parents do not report history of speech and language problems. No sample available for father. All children have special educational needs. (b) Proband 12. Multiple rare variants in KMT2D and STARD9. No family history available but maternal NWR score in normal range. No sample available for father. (c) Proband 30. SYNPR rare stop variant and SEMA6D novel nonsynonymous variant. Parents do not report history of speech and language problems (although mother has low NWR score). Proband has special educational needs. For key for symbols used in this figure, please refer to Fig. 1.

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