Figure 3: IPA Functional analysis of DEGs correlated with viral genes. | Scientific Reports

Figure 3: IPA Functional analysis of DEGs correlated with viral genes.

From: Integrated host and viral transcriptome analyses reveal pathology and inflammatory response mechanisms to ALV-J injection in SPF chickens

Figure 3

(a) Top canonical pathways. More orange indicates more activation while more blue indicates more inhibition of pathways. (b) Downstream disease and biological pathways. (c) Predicted network showing numerous immune related genes around 3 central hubs (NF-κB, IRF1 and IRF7) that are associated with pathogen recognition process. Dotted lines are indirect interactions and solid lines are direct interactions. Genes in red are up-regulated DEGs, genes in green are down-regulated DEGs, and genes in grey are predicted by IPA.

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