Figure 1: OncoScore distribution of ‘Cancer’ and ‘Non-Cancer’ gene sets.
From: OncoScore: a novel, Internet-based tool to assess the oncogenic potential of genes
BoxPlot (a) and frequency histogram (b) of the OncoScore distributions for non-cancer and cancer genes. (a) Each box plot is drawn between the lower and upper quartiles of the distributions with bold black line showing the median value. The OncoScore distributions of ‘Cancer’ and ‘Non-Cancer’ genes are significantly different (Mann-Whitney-Wilcoxon Test: p-value = 2.2e-16). (b) OncoScore frequency distribution plotted by equispaced breaks. (c) OncoScore and (d) Gene Ranker ranking plot of a mixed panel comprising ‘Cancer’ (*) and ‘Non-Cancer’ genes. The horizontal red lines identify the best cut-off classifier threshold models.
