Figure 3 | Scientific Reports

Figure 3

From: Sevoflurane decreases self-renewal capacity and causes c-Jun N-terminal kinase–mediated damage of rat fetal neural stem cells

Figure 3

(a) FITC Annexin V/PI flow cytometry was used to detect the effects of different durations (6 h, 12 h, and 24 h) of 4.8% sevoflurane on FNSCs-mediated apoptosis. (b) Statistical results for Annexin V–positive cells (*P < 0.05, ***P < 0.001). (c) Expression levels of apoptosis-executing protein cleaved caspase-3 and apoptosis-related proteins bcl-2 and bax after exposure to 4.8% sevoflurane for different durations. (d) Statistical results of the expression of cleaved caspase-3 protein from at least three independent experiments (*P < 0.05). (e) Statistical results of the expression of apoptosis-related proteins bcl-2 and bax (*P < 0.05). All data were derived from the results of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001.

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