Figure 3: Distribution of the potential biological functions of Oct4A protein targets in HEY Oct4A KD cells.

The functions of the Oct4A protein targets obtained from the HEY Oct4A KD cells were searched in the literature and categorised according to their potential cancer-related biological functions. (a) Differentially expressed down regulated proteins are summarised as: (i) down regulated cellular proteins, (ii) down regulated secreted proteins, (iii) downregulated tumor xenograft proteins; (b) Differentially expressed up-regulated proteins are summarised as: (i) up-regulated cellular proteins, (ii) up-regulated secreted proteins, (iii) up-regulated tumor xenograft proteins.