Table 3 Up regulated cellular proteins in HEY Oct4A KD cells.
Category | Gene Name | Protein Description | Rsc | *Reference |
|---|---|---|---|---|
Cytoskeletal | PLS1 | Plastin-1 | 7.1 | (Delanote et al., 2005) |
TWF1 | Twinfilin-1 | 5.1 | (Moseley et al., 2006) | |
EPB41L2 | Erythrocyte membrane protein band 4.1-like 2 | 4.5 | (Lu et al., 2004) | |
Tumour suppression | APOA1 | Apolipoprotein A-1 | 5.1 | (Zamanian-Daryoush et al., 2013) |
ETF1 | Eukaryotic release factor 1 | 2.3 | (Dubourg et al., 2002) | |
AHNAK | Desmoyokin | 1.8 | (Lee et al., 2014) | |
Cellular growth/survival | TFRC | Transferrin receptor protein 1 (CD71) | 2.9 | (Habashy et al., 2010) |
DDX3X | ATP-dependant RNA helicase DDX3X | 2.6 | (Lai et al., 2010) | |
EIF4A2 | Eukaryotic initiation factor 4A2 | 1.8 | (Modelska et al., 2015) | |
Drug resistance | TYMS | Thymidylate synthase (EC 2.1.1.45) | 5.1 | (Wang et al., 2007) |
ATP1A1 | Sodium pump subunit alpha-1 | 1.8 | (Stordal et al., 2012) | |
Lipid metabolism | NCEH1 | Neutral cholestrol ester hydrolase 1 | 3.8 | (Chiang et al., 2006) |
PRIC295 | Peroxisome proliferator activated receptor interacting complex protein | 2.6 | (Pyper et al., 2010) | |
Extracellular matrix | PLOD2 | Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 2.1 | (Gilkes et al., 2013) |
Drug sensitivity | PEBP1 (RKIP) | Phosphatidylethanolamine-binding protein 1 | 1.9 | (Li et al., 2014a) |
Immune response | FLNC | Filamin-C | 1.4 | (Marti et al., 1997) |
