Table 1 Physiological parameters.

From: Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer’s disease-like tau pathology

 

Control (n = 6)

STZ LD (n = 7)

STZ LD Ins (n = 8)

STZ HD (n = 8)

STZ HD Ins (n = 8)

STZ HD Hypo (n = 7)

Weight (g)

34.1 ± 6.4

28 ± 5.4

31.2 ± 8.4

23.6 ± 2.6*

23.6 ± 2.5*

22.9 ± 4.4**

Glycemia (mmol/L)

11.6 ± 1.4

29.7 ± 3***

9.9 ± 8.6

25.1 ± 3.3***

12.1 ± 7.1

27 ± 4***

Insulinemia (μg/L)

1.41 ± 0.39

0.14 ± 0.07***

+++

0.03 ± 0.03***

+++

0.009 ± 0.004***

Temperature (°C)

36.9 ± 0.5

36 ± 0.9

36.3 ± 0.7

37.2 ± 0.5

37.2 ± 0.4

34.8 ± 0.6***

  1. Body weight, fasting glycaemia and insulinemia and body temperature. Data are mean ± SD. Asterisks indicate significant differences from controls, with *p < 0.05, **p < 0.01 and ***p < 0.001. Data from physiological parameters following a normal distribution were analyzed with one-way ANOVA of variance followed by a Bonferroni’s post hoc test.