Figure 1
From: Structure of the Ebola virus glycoprotein spike within the virion envelope at 11 Å resolution
Electron microscopy of (a) Negative stained EBOV, (inset showing the virus at higher magnification). A defocus of 2–3 microns was used, thus spikes are visible in low contrast. The yellow arrows point to individual GP spikes. (b) Cryo-EM of EBOV, black “dots” are 10 nm colloidal gold added for focusing. (c) Higher magnification showing individual GP spikes (yellow circles), the viral envelope is indicated by white brackets. The red square shows the relative size of the half-diameter images used for the image processing symmetrical analysis shown in Supplementary Fig. S3. The white square shows the relative size of the images that were used for the image processing data in shown Fig. 2 and Supplementary Fig. S2.
