Figure 2: 3D structure of the EBOV spike.
From: Structure of the Ebola virus glycoprotein spike within the virion envelope at 11 Å resolution
(a) GP trimer with the docked GP1-GP2 structure 5JQ7 shown from various perspectives. The colour scheme for the 3D reconstruction is as follows: orange, distal end of GP spike; yellow, body of GP spike; green, stalk of GP spike; and blue, integrated in viral envelope. The three GP1-GP2 subunits in 5JQ7 are coloured blue, green, and yellow, and toremifene in red. (b) Surface and ribbon displays of 5JQ7 for comparison with (a): C-terminal ends of GP2 are indicated by arrows. (c) Transmembrane densities visible in the low-pass 13.4 Å filtered reconstruction (red arrow, on left) line up with the heptad repeat alpha-helices of the docked GP2 core structure 2EBO (right: red dots).
