Table 4 Factors associated with liver stiffness measurement ≥ 8.0 kPa in univariate and multivariate analyses in patients with non-alcoholic fatty liver disease.
From: Transient elastography as a screening tool for liver fibrosis in a large hemodialysis population
Variables | Univariate analysis | P Value | Multivriate analysis | P Value |
|---|---|---|---|---|
OR (95% CI) | OR (95% CI) | |||
Age, years | 1.03 (1.00–1.06) | 0.078 | 1.02 (0.97–1.06) | 0.47 |
Male | 1.15 (0.62–2.14) | 0.657 | 1.33 (0.55–3.20) | 0.53 |
BMI | ||||
Normal; BMI <24 (kg/m2) | 1.00 (reference) | 1.00 (reference) | ||
Overweight; 24 ≤ BMI < 30 (kg/m2) | 2.49 (1.29–4.81) | 0.006 | 4.13 (1.69–10.10) | 0.002 |
Obese; BMI ≥30 (kg/m2) | 3.18 (0.87–11.61) | 0.079 | 9.44 (1.80–49.49) | 0.008 |
DM (%) | 1.00 (0.54–1.88) | 0.992 | 0.64 (0.28–1.42) | 0.27 |
AST (IU/L) | 1.11 (1.06–1.17) | <0.001 | 1.21 (1.11–1.31) | <0.001 |
ALT (IU/L) | 1.02 (0.99–1.05) | 0.218 | 0.93 (0.87–0.99) | 0.02 |
Bilirubin (mg/dL) | 3.51 (0.45–27.23) | 0.230 | 8.02 (0.46–139.24) | 0.15 |
Albumin (mg/dL) | 0.43 (0.17–1.11) | 0.080 | 0.48 (0.13–1.78) | 0.27 |
Creatinine (mg/dL) | 0.95 (0.84–1.08) | 0.407 | 0.98 (0.80–1.20) | 0.85 |
Platelet (109/L) | 1.00 (0.99–1.00) | 0.097 | 1.00 (0.99–1.00) | 0.18 |
HDL-C: <40 mg/dL(male) or <50 mg/dL(female) | 2.03 (0.98–4.20) | 0.058 | 1.83 (0.69–4.85) | 0.22 |
LDL (mg/dL) | 0.99 (0.98–1.00) | 0.034 | 0.99 (0.96–1.01) | 0.21 |
Triglyceride >150 (mg/dL) | 1.51 (0.80–2.87) | 0.207 | 1.20 (0.42–3.43) | 0.74 |
Total cholesterol (mg/dL) | 0.99 (0.98–1.00) | 0.093 | 1.00 (0.98–1.03) | 0.64 |
Steatosis | ||||
Steatosis grade 1 (232.5 ≥CAP <255) (dB/m) | 1.00 (reference) | 1.00 (reference) | ||
Steatosis grade 2 (255 ≥ CAP <290) (dB/m) | 2.26 (0.96–5.32) | 0.062 | 2.20 (0.80–6.03) | 0.13 |
Steatosis grade 3 (≥290) (dB/m) | 3.64 (1.55–8.55) | 0.003 | 2.94 (1.00–8.63) | 0.05 |
