Table 2 Differentially accumulated proteins not reported in the HDDP lists that were identified in Mexican patients with diabetes.

From: 2D-DIGE as a strategy to identify serum biomarkers in Mexican patients with Type-2 diabetes with different body mass index

ID	Spots in DIGE gels^a	Name of Protein^b	Accession Number^c	Tendency^d
Low-abundance protein fraction
1	3, 8, 10, 29, 42, 57	Alpha-1B-glycoprotein	A1BG_HUMAN	Di Dd
2	56	Alpha-2-antiplasmin	A2AP_HUMAN	Dd
3	25, 34, 41	Leucine-rich alpha-2-glycoprotein	A2GL_HUMAN	Di Dd
4	5U, 34, 9, 25, 13, 5729, 47,	Alpha-1-antichymotrypsin	AACT_HUMAN	Oi, Di Dd, P
5	53	AMBP	AMBP_HUMAN	P
6	29, 57	Antithrombin-III	ANT3_HUMAN	Dd
7	40, 47, 51	Beta-2-glycoprotein 1	APOH_HUMAN	Di
8	1, 9, 4, 1115, 39, 55	Coiled-coil domain-containing protein 87	CCD87_HUMAN	Di P DOi Od Oi
9	1431, 35	Clusterin	CLUS_HUMAN	P Di
10	3, 36, 5341	Complement C4-A	CO4A_HUMAN	Di Dd
11	8, 22, 2845	Complement C4-B	CO4B_HUMAN	Di DOd
12	3637	Glutathione peroxidase 3	GPX3_HUMAN	Di Dd
13	3, 10, 25, 29, 45, 13, 36, 44, 15, 16, 22, 28, 41, 46U, 47, 48, 57	Hemopexin	HEMO_HUMAN	Di DOd, Od Oi, P, DOi, Dd
14	31	Histidine-rich glycoprotein	HRG_HUMAN	Di
15	48	Plasma protease C1 inhibitor	IC1_HUMAN	DOi
16	11, 32, 52, 36, 42, 5653	Inter-alpha-trypsin inhibitor heavy chain H4	ITIH4_HUMAN	DOi Di Dd P
17	9, 14, 29, 47, 32, 42, 5752	Kininogen-1	KNG1_HUMAN	Di P DOi Dd DOi
18	48	Lymphoid-restricted membrane protein	LRMP_HUMAN	DOi
19	36	MAGUK p55 subfamily member 2	MPP2_HUMAN	Di
20	10	Rhox homeobox family member 1	RHXF1_HUMAN	Di
High-Abundance protein fraction
21	26U, 37 36	Zinc-alpha-2-glycoprotein	ZA2G_HUMAN	Dd Di
22	22 24	14-3-3 protein beta/alpha	1433B_HUMAN	Di Dd
23	14	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2	ASAP2_HUMAN	Di
24	34	Haptoglobin-related protein	HPTR_HUMAN	Dd
25	8	Oncoprotein-induced transcript 3 protein	OIT3_HUMAN	Di
26	37	Otopetrin-3	OTOP3_HUMAN	Od
27	43	Trinucleotide repeat-containing gene 6C protein	TNR6C_HUMAN	Dd

^aSpots numbers as indicated in Supplementary Files 1–3 where details including protein score, ion score, and peptide coverage are provided.
^bName of the protein and ^cAccession number according to Homo sapiens(human) database from SwissProt(2015).
^dTendency of protein accumulation in different diabetic groups as indicated in Supplementary Files 1–3.
D = diabetes; O = obesity; DO = diabetes and obesity; P = punctual variation; i = increases; d = decreases.

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Table 2 Differentially accumulated proteins not reported in the HDDP lists that were identified in Mexican patients with diabetes.

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