Figure 3 | Scientific Reports

Figure 3

From: Spatiotemporally and Sequentially-Controlled Drug Release from Polymer Gatekeeper–Hollow Silica Nanoparticles

Figure 3

(A,D) Zeta potential measurement of PHMSNs and PEG–PDS-wrapped HMSNs in buffers with varying pH values for 24 mol% and 56 mol% crosslinked PHMSN. (B,E) CPT–Dox dual drug release profile of PHMSNs at different pH values for 24 mol% and 56 mol% crosslinked PHMSN. (C,F) Size analysis of PHMSN in buffer solutions with different pH values at 24 mol% and 56 mol% crosslinked PHMSN. (G) Schematic of charge reversal, volume change of polymer-shell and sequential drug release upon the change in pH and glutathione concentration.

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