Figure 5 | Scientific Reports

Figure 5

From: Spatiotemporally and Sequentially-Controlled Drug Release from Polymer Gatekeeper–Hollow Silica Nanoparticles

Figure 5

Images of in vitro cellular uptake of dual drug-loaded PHMSNs by KB cells after incubation at (A) pH 6.5 and (B) pH 7.4 DPBS. (C) Fluorescence-activated cell sorting analysis of cellular uptake of PHSMNs at pH 7.4 (red line), pH 6.5 (blue line), and in normal cell culture medium (green) after 2 h of incubation. (D) In vitro cytotoxicity analysis of KB cells incubated with dual drug-loaded PHMSNs at different pH, and (E) with pristine HMSN and PHMSN. Scale bar represents 20 μm.

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