Table 3 Identification of CD4BS directed antibodies in BCN plasma samples.

From: Broad and potent cross clade neutralizing antibodies with multiple specificities in the plasma of HIV-1 subtype C infected individuals

Samples ID

Mean absorbance at 450 nm

Binding Difference between RSC3 and RSC3Δ371I/P363N proteins

P value

% of RSC3 binding antibodies in the BCN plasma samples

RSC3 protein

RSC3D371I/P363N protein

NAB001

0.214

0.267

−0.053

P > 0.05

ND

NAB004

0.154

0.147

0.007

P > 0.05

ND

NAB016

0.1585

0.145

0.0135

P > 0.05

ND

NAB033

0.361

0.161

0.2

P < 0.05

55

NAB046

0.268

0.312

−0.044

P > 0.05

ND

NAB059

1.089

0.6515

0.437

P < 0.001

40.2

NAB062

0.2805

0.1945

0.086

P > 0.05

ND

NAB063

1.87

1.265

0.6055

P < 0.001

32.3

NAB065

0.084

0.153

−0.069

P > 0.05

ND

NAB069

2.31

0.2085

2.102

P < 0.001

91

NAB120

0.1475

0.1615

−0.014

P > 0.05

ND

NAB122

0.237

0.1525

0.0845

P > 0.05

ND

Control (HHP)

0.075

0.079

−0.0045

P > 0.05

NA

  1. Samples having CD4BS directed antibodies are highlighted in bold. p < 0.05 is considered significant.
  2. N.D., Not Detectable; N.A., Not Applicable.
Back to article page