Table 9 Neutralization activity of MPER-specific IgG against tier-2 pseudovirus panels.

From: Broad and potent cross clade neutralizing antibodies with multiple specificities in the plasma of HIV-1 subtype C infected individuals

polyclonal IgG eluted by MPER peptide

IC50 μg/ml

Name of pseudoviruses

Tier-2 subtype B

Tier-2 subtype C

control virus

JR-FL

RHPA

CAP210

pIndie

MuLV

NAB069

14.16

>40

13.6

9.2

>40

NAB122

14.80

14.40

16.0

10

>40

HHP

>40

>40

>40

>40

>40

  1. Neutralization titer (IC50) assay was performed with IgG antibody (concentrations 40 to 0.0004 μg/ml) eluted using MPER-peptide coated tosyl activated MyOne Dynabeads against four HIV-1 pseudoviruses and MuLV
  2. IC50 values <20 μg/ml are shown in bold format and values >20 μg/ml are shown in normal format.
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