Figure 5: LncRNA/mRNA transcripts co-expression network after SAH. | Scientific Reports

Figure 5: LncRNA/mRNA transcripts co-expression network after SAH.

From: High-Throughput Sequencing and Co-Expression Network Analysis of lncRNAs and mRNAs in Early Brain Injury Following Experimental Subarachnoid Haemorrhage

Figure 5

(A) The network represents the co-expression correlations between the significantly differentially expressed mRNA and lncRNA transcripts (|COR| > 0.95, P < 0.05). Circles indicate lncRNA transcripts and triangles indicate mRNA transcripts. Solid lines indicate positive correlations, and dashed lines indicate negative correlations. Red represents upregulated, and green represents downregulated. (B) KEGG analysis suggested that lncRNA-coexpressed mRNAs were mainly targeted to the Toll-like receptor signaling pathway (http://www.genome.jp/kegg)54,55. Blue represents significant genes in this pathway of SAH, and pentagrams represent significant lncRNA-coexpressed genes.

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