Figure 1: Genes vs genome plot representing non-synonymous variations of 890 metabolic genes, divided into 116 in silico Essential Genes (IEG), 211 Metabolic Persister Genes (MPG) and other genes(563) of Mtb in 1623 sequenced clinical isolates (white dots indicate the presence of non-synonymous variation).

Least and most mutated 5 genes from each group are shown along the rv ID indices axis.