Table 3 Meta-analysis of the association between LMR and clinicopathological features of HCC.
Characteristics | No. of studies | No. of patients | OR (95% CI) | p | Heterogeneity | |
|---|---|---|---|---|---|---|
I2 (%) | Ph | |||||
Gender (male vs. female) | 3 | 913 | 1.16 (0.64–2.09) | 0.62 | 54 | 0.11 |
AFP (>400 ng/mL vs. <400 ng/mL) | 2 | 660 | 1.61 (0.81–3.20) | 0.17 | 73 | 0.05 |
Liver cirrhosis (yes vs. no) | 3 | 913 | 1.66 (0.97–2.83) | 0.06 | 52 | 0.12 |
Differentiation (low vs. moderate/high) | 3 | 913 | 1.04 (0.74–1.46) | 0.82 | 0 | 0.88 |
Tumor number (multiple vs. single) | 2 | 660 | 0.96 (0.62–1.50) | 0.87 | 0 | 0.61 |
Tumor size (>5 cm vs. <5 cm) | 3 | 913 | 1.36 (0.79–2.35) | 0.27 | 69 | 0.04 |
TNM stage (III-IV vs. I-II) | 2 | 703 | 1.78 (1.19–2.68) | 0.005 | 33 | 0.29 |
BCLC stage (B/C vs. A) | 2 | 703 | 1.70 (1.21–2.39) | 0.002 | 0 | 0.38 |
Vascular invasion (pos vs. neg) | 2 | 660 | 1.47 (0.48–4.49) | 0.50 | 84 | 0.01 |
