Table 3 Univariate logistic regression analysis of clinical and laboratory parameters, and 3-month mortality.

From: Serum Concentration of HDL Particles Predicts Mortality in Acute Heart Failure Patients

Variable

Category

OR (95% CI) per 1 SD

p-value

Events

Age (years)

 

1.37 (0.94–2.08)

0.114

40/146

Sex

male

Ref.

 

16/70

 

female

1.56 (0.75–3.30)

0.239

24/76

BMI (kg/m2)

 

0.70 (0.47–1.02)

0.074

40/146

Hypertension

no

Ref.

 

7/16

 

yes

0.44 (0.15–1.31)

0.128

33/130

Type 2 Diabetes Mellitus

no

Ref.

 

21/69

 

yes

0.76 (0.36–1.58)

0.465

19/76

MAP (mmHg)

 

0.56 (0.36–0.84)

0.007

40/146

NYHA class

2 and 3

Ref

 

20/90

 

4

1.94 (0.93–4.09)

0.078

20/56

EF (%)*

>40

Ref

 

14/71

 

≤40

1.44 (0.65–3.26)

0.373

17/65

Total cholesterol (mmol/L)

 

0.53 (0.33–0.80)

0.005

40/146

LDL-c (mmol/L)

 

0.56 (0.34–0.85)

0.011

40/146

HDL-c (mmol/L)

 

0.69 (0.43–1.05)

0.107

40/146

Triglycerides (mmol/L)

 

0.74 (0.46–1.10)

0.172

40/146

Large VLDL-p (nmol/L)

 

0.43 (0.15–0.91)

0.066

20/74

Total LDL-p (μmol/L)

 

0.68 (0.44–1.02)

0.075

37/130

Large LDL-p (μmol/L)

 

0.63 (0.38–0.98)

0.057

34/121

Small LDL-p (μmol/L)

 

0.89 (0.58–1.30)

0.561

36/127

Total HDL-p (μmol/L)

 

0.38 (0.23–0.60)

<0.001

37/130

Large HDL-p (μmol/L)

 

1.22 (0.79–1.88)

0.353

30/103

Small HDL-p (μmol/L)

 

0.35 (0.19–0.60)

<0.001

27/110

GFR (ml/min/1.73 m2)

 

0.60 (0.39–0.88)

0.012

39/145

Creatinine (mol/L)

 

1.44 (1.02–2.06)

0.039

39/145

Urea (mmol/L)

 

1.61 (1.13–2.39)

0.013

39/145

NT-proBNP (pg/mL)

 

1.92 (1.32–2.93)

0.001

38/135

CRP (μg/mL)

 

1.18 (0.83–1.68)

0.341

40/145

  1. For continous variables ORs are presented per standard deviation increment. Significant associations are depicted in bold. BMI = Body Mass Index; CI = confidence interval; CRP = C-reactive protein; EF = Ejection Fraction; Events = number of events/total number of patients in category; GFR = glomerular filtration rate; HDL-c = high density lipoprotein cholesterol; HDL-p = HDL particle concentration; LDL-c = low-density lipoprotein cholesterol; LDL-p = large LDL particle concentration; n = number of samples in which particular parameter was analysed; MAP = Mean Arterial Pressure; NT-proBNP = N-terminal pro-Brain Natriuretic Peptide; NYHA = New York Heart Association Functional Classification; OR = odds ratio; Ref. = reference category; SD = standard deviation; VLDL-p = very low-density lipoprotein particle concentration.