Figure 5: Decrease in eicosanoid precursors in NASH. | Scientific Reports

Figure 5: Decrease in eicosanoid precursors in NASH.

From: Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients

Figure 5

Hepatic levels of (a) arachidonic acid (C20:4n-6), eicosapentanoic acid (C20:5n-3), and docosahexaenoic acid (C22:6n-3) in the patients studied (upper panel) and mouse models (lower panel). (b) Total phospholipids in each group of patients. Data are means ± SEM. *p < 0.05, by unpaired t-test compared to Control group and †p < 0.05, by unpaired t-test compared to NAFL groups after ANOVA analysis. Control n = 7; NAFL1 n = 9; NAFL2 n = 12; NAFL3 n = 18; NASH_Lds n = 15; NASH_Vds n = 7 and Control n = 10; HFD n = 5; MCDD n = 5.

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