Figure 5: Visual characterization of the aggregation behaviour of AMTN and ODAM. | Scientific Reports

Figure 5: Visual characterization of the aggregation behaviour of AMTN and ODAM.

From: Interactions of AMTN, ODAM and SCPPPQ1 proteins of a specialized basal lamina that attaches epithelial cells to tooth mineral

Figure 5

(a–c) Transmission electron microscopy (TEM) of negative stain and (d–f) atomic force microscopy preparations of purified AMTN and ODAM demonstrate the propensity of the proteins to self-interact into globular complexes. Mixing the two proteins together generates larger complexes suggesting heterologous interactions. (Insets in a,b) Observation of the complexes under native conditions by cryo-TEM confirms that they do not result from preparation artefacts.

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