Table 1 Validated mutations in K150/B150 of experimental evolution.

From: Comparative genomics and metabolomics analyses of the adaptation mechanism in Ketogulonicigenium vulgare-Bacillus thuringiensis consortium

Species	Gene	Gene function	Mutation	Genome position/bp	Substitution
K150	ffh	signal recognition particle protein	C → T	201775	V → M
	KVH_05035	creatinine amidohydrolase	T → C	1003977	I → M
	hipO	amidohydrolase	G → A	1443879	G → S
	KVH_08735	NADPH nitroreductase	A → C	1743506	S → A
	dksA	RNA polymerase-binding protein DksA	G → A	2006178	R → C
B150	BtBc_02850	epimerase	C → T	550413	W → U
	BtBc_03145	chemotaxis protein	A → G	602604	Q → R
	treR	trehalose operon repressor	A → G	692130	Q → R
	yfnA	amino acid permease	C → T	917190	C → Y
	BtBc_04905	MarR family transcriptional regulator	G → A	932415	T → I
	BtBc_08920	hypothetical protein	C → T	1691716	M → I
	BtBc_08990	glycosyltransferase	A → G	1703700	T → A
	BtBc_12015	TetR family transcriptional regulator	A → G	2307900	M → T
	azr	NADPH-dependent FMN reductase	C → T	2370384	P → S
	lsrB	autoinducer 2-binding protein lsrB	T → A	2890716	S → T
	hutH	histidine ammonia-lyase	C → T	3779434	A → T
	polC	PolC-type DNA polymerase III	T → C	3942021	K → E
	greA	transcription elongation factor GreA	T → C	4475438	E → G
	hemA	glutamyl-tRNA reductase	T → C	4563120	H → R
	BtBc_24035	histone deacetylase	G → A	4743005	R → Q
	mviM	virulence factor MviM	A → G	4759919	Q → R
	ftsK	cell division protein FtsK	C → T	4773874	V → I
	BtBc_26105	serine/threonine protein kinase	G → A	5114831	A → V
	BtBc_27510	glycosyl transferase	C → T	5387774	W → U
	rho	transcription termination factor Rho	G → A	5448060	P → L
	BtBc_27985	LPXTG-domain-containing protein cell wall anchor domain	C → G	5485786	A → G
	BtBc_28330	glycosyl transferase family	T → C	5557300	S → P
	BtBc_30195	hypothetical protein	Delete T	1655	shift
	BtBc_30200	hypothetical protein	Insert A	2920	shift
	BtBc_08255	ribosomal protein L5 domain protein	Delete A	1568624	shift
	BtBc_08685	uracil-DNA glycosylase	Delete A	1648698	shift
	BtBc_09325	motility repressor MogR	Delete A	1775506	shift
	BtBc_12210	molecular chaperone Hsp20	Delete T	2343900	shift
	bacF	non-ribosomal peptide synthetase	Delete A	2446926	shift
	BtBc_16740	S-adenosylhomocysteine nucleosidase	Delete T	3298277	shift
	BtBc_18345	Lsa family ABC-F type ribosomal protection protein	Insert AT	3629982	shift
	BtBc_18600	spore germination protein	Insert A	3689846	shift

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Table 1 Validated mutations in K150/B150 of experimental evolution.

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