Figure 2
From: Decanalization, brain development and risk of schizophrenia
The epigenetic landscape. The upper panel (a) shows an optimal developmental trajectory, with a range of expected instructions (red and green arrows) contributing over time to maintain the desired trajectory. The middle panel (b) shows how the absence of expected instructions during early development (unbalanced arrows in the top of the figure) can decanalize development. The lower panel (c) shows how an unexpected instruction (large blue arrow) can also lead to decanalization of development.
