Table 1 List of known compounds quantified by the LCECA platform

From: Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept

Metabolite by pathways

Abbreviation

Metabolite by pathways

Abbreviation

Tryptophan

 

Phenylalanine

 

 3-Hydroxykynurenine

3-OHKY

 2-Hydroxyphenylacetic acid

2-HPAC

 5-Hydroxyindoleacetic acid

5-HIAA

 4-hydroxybenzoic acid

4-HBAC

 5-Hydroxytryptophan

5-HTP

 4-Hydroxyphenyllactic acid

4-HPLA

N-acetylserotonin

NA5HT

Purine

 

 Anthranilic acid

ANA

 7-Methylxanthine

7-MXAN

 Indole-3-lactic acid

I3LA

 Guanosine

GR

 Indoleacetic acid

IAA

 Hypoxanthine

HX

 Indolelactic acid

ILA

 Hypoxanthine/xanthine

HX/XAN

 Kynurenine

KYN

 Uric acid

URIC

 Melatonin

MEL

 Xanthine

XAN

 Serotonin

5-HT

 Xanthosine

XANTH

 Tryptophan

TRP

 7-Methylguanine

7-MG

 Tryptophol

TPOL

 Guanosine monophosphate

GRMP

 5-methoxytryptophol

5-MTPOL

Glutamate, cysteine, glutathione

 

Tyrosine

 

 Glutathione (oxidized)

GSSG

 3-O-methyldopa

3-OMD

 Glutathione (reduced)

GSH

 4-Hydroxyphenylacetic acid

4-HPAC

 Cysteine

CYS

 Dihydroxymandellic acid

DIOLMAL

Biosynthesis of steroids, vitamin E

 

 Dihydroxyphenylacetic acid

DOPAC

 Tocopherol-alpha

ATOCO

 Homogentisic acid

HGA

 Delta tocopherol

DTOCO

 Homovanillic acid

HVA

 Tocopherol

TOCO

 L-Dopa

LD

 Tocopherol-gamma

GTOCO

 Methoxy-hydroxyphenly glycol

MHPG

Ascorbate

 

 Tyramine

TYRA

 Ascorbate

ASC

 Tyrosine

TYR

One carbon metabolism

 

 Vanillylmandelic acid

VMA

 Methionine

MET

Exogenous drug

 

Other

 

 Salicylate

SAL

 Vanillic acid

VANA