Figure 2
Mean COX-2 (a), COX-1 (b), mPGES-1 (e) and cPGES-2 (f) protein (with representative immunoblots) as percent of control in frontal cortex, from control (n=10) and AD (n=10) subjects. Data are optical densities with relative to that of β-actin. COX-2 (c), COX-1 (d) mPGES-1 (g) and cPGES-2 (h) mRNA levels in the frontal cortex from controls (n=10) and AD patients (n=10), measured using RT-PCR. Data are normalized to the endogenous control (β-globulin) and expressed with relative to the control (calibrator), using the ΔΔCT method. Mean±s.e.m., *P<0.05 and **P<0.01.
