Table 1 Characteristics of control subjects and patients with Alzheimer's disease

From: Altered neuroinflammatory, arachidonic acid cascade and synaptic markers in postmortem Alzheimer’s disease brain

Group

Age (years)

Sex

PMI (h)

Cause of death

Medications

Disease stage

Genotype

Control

60

F

21

Cardiopulmonary attack

Aspirin

 

ApoE2/4/

ApoE2/3

Control

80

M

15

Myocardial infarction

Furosemide

 

ApoE2/4

ApoE2/3

Control

79

F

19

Cardiopulmonary attack

Isosorbide

 

ApoE2/4

ApoE2/3

Control

72

M

22

Cardiopulmonary attack

Atorvastatin

 

ApoE2/4 ApoE2/3

Control

64

M

15

Acute myocardial infarction

Vitamins

 

ApoE2/4

ApoE2/3

Control

74

M

18

Cardiac arrest

Atenolol and digoxin

 

ApoE2/4

ApoE2/3

Control

61

M

22

Myocardial infarction

Vitamins

 

ApoE2/4

ApoE2/3

Control

78

F

17

Myocardial infarction

Atorvastatin

 

ApoE2/4

ApoE2/3

Control

63

M

15

Heart failure

Furosemide

 

ApoE2/4

ApoE2/3

Control

71

M

23

Cardiac arrest

Aspirin

 

ApoE2/4

ApoE2/3

AD

76

F

25

Stroke

Sertraline, carbamazepine, alendronate and aspirin

V

ApoE4/4

AD

83

M

17

Stroke

Donepezil, valproate, tamsulosin and escitalopram

V

ApoE4/4

AD

72

M

24

AD

Atenolol, donepezil, valproate and alprazolam

VI

ApoE4/4

AD

78

F

17

AD

Fexofenadine, donepezil and aspirin

VI

ApoE4/4

AD

75

M

15

Atherosclerosis

Gabapentin, furosemide, quetiapine and escitalopram

VI

ApoE2/4

ApoE2/3

AD

66

M

23

Broken hip and AD

Rivastigmine and donepezil

V

ApoE2/4

ApoE2/3

AD

63

M

18

Pneumonia

Carbamazepine, sertraline, aspirin and quetiapine

VI

ApoE2/4

ApoE2/3

AD

71

M

16

End of AD

Atorvastatin, donepezil, pantoprazole, verapamil, vitamin E and risperidone

VI

ApoE2/4

ApoE2/3

AD

61

F

21

End of AD

Pantoprazole, verapamil, vitamin E and risperidone

VI

ApoE2/4

ApoE2/3

AD

61

M

17

Pneumonia

Valproate, quetiapine and olanzapine

VI

Not available

  1. Abbreviations: AD, Alzheimer’s disease; F, female; M, male; PMI, postmortem interval.
  2. Not available, sample volume was not enough for this experiment; staging was done according to Reisberg et al.40