Figure 1
From: Increased de novo copy number variants in the offspring of older males
Relative copy number (rCN) in the combined samples established by Sequenom. rCN in the combined samples was examined by Sequenom competitive quantitative PCR. The data from both sets of animals are shown with all values scaled to set a relative CN of 1 at 0. (a) Variation in CNV2 was established using three separate assays targeting the 5′ prime, central or 3′ prime region of this CNV, respectively. (b) The remaining CNVs were detected by one assay, each. CNV2–CNV6: Boxes denote positive calls for amplifications or deletions. No formal assignment of calls was performed for the highly variable loci CNV1 and CNV7. CNV, copy number variant.
