Figure 3 | Translational Psychiatry

Figure 3

From: Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype

Figure 3

Shown is a graph of IL-1β, IL-6, IL-8 and TNFα levels in stimulated whole-blood supernatants taken from HC (Ctrl), schizophrenia (Scz) and bipolar (BP) patients measured using enzyme-linked immunosorbent assay following treatment with (a) TLR5 agonist Flagellin, (b) TLR6/2 agonist FSL1, (c) TLR7 agonist Imiquimod, (d) TLR8 agonist ssRNA40 or (e) TLR9 agonist ODN2006 for 24 h. Data shown are expressed as mean±s.e.m. Statistical differences between treatments and untreated were determined using two-way ANOVA with Bonferroni post-hoc test. *P<0.05, ***P<0.001 vs Ctrl; #P<0.05, ##P<0.01, bipolar disorder vs schizophrenia.

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