Table 2 Relationship between severity of obsessions and compulsions and subthalamic neuronal activity in OCD patients

From: Basal ganglia dysfunction in OCD: subthalamic neuronal activity correlates with symptoms severity and predicts high-frequency stimulation efficacy

 

Y-BOCS

Obsessions

Compulsions

Mean discharge frequency

0.46

0.54

0.31

Burst discharges

   

 Mean burst (S) index

−0.32

−0.40

−0.32

 Mean burst frequency

0.02

0.14

−0.03

 Mean burst duration

−0.46

−0.60*

−0.40

 Mean intraburst frequency

0.68*

0.78*

0.60*

 Mean interburst interval

−0.55

−0.65*

−0.58*

δ band (1–4 Hz)

   

 Mean proportion of neurons

0.11

−0.13

0.37

 Mean peak frequency

0.79*

0.81*

−0.08

 Mean power peak frequency

0.38

0.61*

−0.02

θ band (4–8 Hz)

   

 Mean proportion of neurons

−0.48

−0.50

−0.05

 Mean peak frequency

−0.07

0.01

−0.11

 Mean power peak frequency

0.17

0.10

0.38

α band (8–12 Hz)

   

 Mean proportion of neurons

−0.45

−0.45

0.73*

 Mean peak frequency

−0.12

0.06

−0.62*

 Mean power peak frequency

−0.26

0.02

−0.85*

β-low band (12–20 Hz)

   

 Mean proportion of neurons

−0.56

−0.04

−0.02

 Mean peak frequency

0.02

−0.33

0.01

 Mean power peak frequency

−0.26

0.34

−0.07

β-high band (20–35 Hz)

   

 Mean proportion of neurons

−0.50

−0.30

0.12

 Mean peak frequency

−0.04

−0.10

−0.27

 Mean power peak frequency

0.40

0.27

0.20

γ band (>35 Hz)

   

 Mean proportion of neurons

−0.22

0.03

−0.49

 Mean peak frequency

−0.32

0.11

−0.01

 Mean power peak frequency

−0.32

−0.34

−0.40

  1. Abbreviations: OCD, obsessive–compulsive disorder; Y-BOCS, Yale–Brown Obsessive–Compulsive Scale.
  2. Values are correlation coefficients (non-parametric Spearman's regression). Entries shown in bold *P<0.05 after univariate analysis.
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